Outlook Saying Something Went Wrong Please Try Again Later – Solved

  

Mark Regan
Published: September 19th, 2025 • 7 Min Read

As many Outlook users have recently reported about Microsoft Outlook Error 0x80049dd3 when trying to send or receive emails. As we noticed a growing number of people searching for this error on Microsoft Forums and Community platforms. So, we have decided to write a detailed guide to explain the causes and methods to continue to use Outlook without facing any error.

New Outlook or Outlook 0x80049dd3 Sign in Error is a common error code that usually appears when Outlook is available to connect to the mail server or when there is a problem with account configuration. This error can prevent you from accessing your emails smoothly and may disrupt regular communication.

Microsoft Outlook Error 0x80049dd3 must appear due to incorrect account settings, corrupted Outlook data files(OST/PST), or server connection issues. In some cases, outdated Outlook versions, antivirus issues or poor connectivity may also be the reasons for Microsoft Outlook Error 0x80049dd3.

Common Causes of Microsoft Outlook Error 0x80049dd3

• One of the most frequent reasons behind Microsoft Outlook Error 0x80049dd3 is misconfigured settings. If your incoming IMAP/POP3 or outgoing SMTP server details are correct, Outlook will fail to establish connection, resulting in this error code.
• When Outlook files become larger then Outlook may struggle to access mailbox data. This corruption is also the reason for Microsoft Outlook Error 0x80049dd3 and preventing email synchronization.
• If your connectivity is not stable or the mail server is temporarily down, Outlook may not send or receive emails. This interruption is another common reason for Microsoft Outlook Error 0x80049dd3.
• Using older versions of Outlook or using incompatible versions can also create performance issues. Outdated versions are also the prime reasons to stop sending or receiving Outlook emails.
• Security software sometimes blocks Outlook from connecting to the mail server. Overly strict antivirus or firewall settings may mistakenly treat Outlook as a threat, causing Microsoft Outlook 0x80049dd3 login error.

How to Fix Microsoft Outlook Error 0x80049dd3?

Method 1. Verify Outlook Email Account Settings

1. Open Outlook and navigate to the file.
   
2. Click on Account Settings and again tap on Account Settings in the dropdown list.
   
3. Select your email account and tap on Change.
   
4. Check the Incoming Mail Server(IMAP/POP3) and Outgoing Mail Server(SMTP details).
5. Verify Port Number and Encryption Method(SSL/TLS) match the details provided by your email provider.
6. Click on Next and then finish to Save Changes.

Method 2. Repair Corrupted OST or PST Files

1. Close Outlook completely.
2. Locate ScanPST.exe(Outlook Inbox Repair Tool) in your Outlook installation folder.
3. Double-click ScanPST.exe and browse to select your PST file.
   
4. Click Start to scan the file.
   
5. If errors are found, click on Repair.
   
6. Restart Outlook and check if Microsoft Outlook Error 0x80049dd3 is resolved.

Method 3. Check Internet and Server Connectivity

1. Make sure the connection is stable.
2. Open a Web Browser and login to your email providers webmail to confirm server availability.
3. If Webmail works but Outlook doesn’t , try restarting your router.
4. Reopen Outlook and check if the error persists.

Method 4. Update Microsoft Outlook and Windows

1. Open Outlook and navigate to the file.
   
2. Click on Office Account and hit on Update Options.
   
3. Tap on Update Now and allow Outlook to install the latest updates.
   
4. On Windows, press Win+I and select Update and Security and tap on Windows Update.
5. Click on Check for Updates and install Pending Updates.
6. Relaunch your pc and start Outlook.

Method 5. Disable Antivirus or Firewall Temporarily

1. Right-click on your Antivirus Program in the taskbar.
2. Select Disable Selection(choose a short duration as 15 minutes).
3. Try Sending/Receiving emails in Outlook.
4. If the error disappears, add Outlook.exe to your Antivirus/firewall exception list.
5. Re-enable your Antivirus for security.

Method 6. Create a New Outlook Profile

1. Close Outlook.
2. Open the Control Panel and hit Mail(Microsoft Outlook).
   
3. Hit on Show Profiles and select Add and fill profile name, and configure your email account.
   
4. Now Set New Profile as default.
   
5. Open Outlook with the new profile and check if the error is resolved.

Method 7. Use Safe Mode to Troubleshoot Add-ins

1. Press Win+R to open the Run dialog box.
2. Type Outlook.exe/safe and hit Enter.
   
3. Outlook will launch in Safe Mode.
4. If the error doesn’t appear, navigate to file and click on options.
   
5. Tap on Add-ins and disable suspicious Add-ins by selecting COM Add-ins and tap on Go.
   
6. Uncheck faulty Add-ins and reopen Outlook.
   

Key Features of Recommended Tool

• It allows to repair batch Outlook files and also can repair and convert PST to PDF, EML, EMLX, PDF, MBOX and many more.
• This tool specially creates a simple initiative interface to make it friendly for all levels of users.
• You can also repair and import PST to Thunderbird, Office 365, Zimbra and many more for maintained attributes.
• With this wizard, users can easily export repaired PST files at any destination as it offers complete destination flexibility.
• This software offers UNICODE PST file to easily access in all the versions of Microsoft Outlook.

Preventing Microsoft Outlook Error 0x80049dd3

• Keep Outlook and Windows update to fix bugs and offer faster performance from previous versions and it helps to fix Microsoft Outlook Error 0x80049dd3.
• Regularly compact OST file and create backups. Optimised data files reduce the chances of corruption that could trigger Microsoft Outlook Error 0x80049dd3.
• Adds Outlook as an Exception in your Antivirus or firewall. Check security features to prevent blocked Outlook connection and come Microsoft Outlook Error 0x80049dd3.
• Avoid closing Outlook properly before shutting down your computer. Abrupt shutdowns may corrupt data files, leading to recurring issues like Microsoft Outlook Error 0x80049dd3.

Final Thoughts

Let’s conclude this article as users can easily solve this problem by following the given methods. However, if errors will not resolve manually, then it mostly happens due to bad factors in Outlook files. In this situation, you need to try an Advanced solution as it can restore Outlook files and offer continued use of error-free Outlook.